Treating Eosinophils Count in Asthma

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Asthma is a multifactorial disease, caused by meany inflammatory mediators that are being explored and described. Usually, when patients do not respond to traditional long acting beta agonist and steroids means they have excess inflammatory interleukins that contribute to asthma. These include interleukin 4, 5 and 13, associated with Th2 cells or allergic asthma.

However, not all allergies that are measured by allergists may explain the causes of asthma.

There are three new medications that treat eosinophils or white blood cells count that stain red, and are affiliated with allergy. These medications are Fasenra, Nucala or Cinguair. Thet lower eosinophils count in the blood and improve asthma outcomes and exacerbations. Another drug, Dupixent, inhibits interleukin 4 and interleukin 13. With this combination this medication also lowers eosinophils and correlates with asthma. Patients who do not respond to this medication may have neutrophilic asthma or white blood cell that do not stain red. These patients have less response to prednisone when they have exacerbations of their asthma.


If you need to book an appointment for your allergies or asthma, you can book your appointment online, or call 212-247-7447.

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